According to researchers working at a Boston women’s hospital an immunosuppressant drug called Sirolimus can help with mesothelioma treatment. Mesothelioma is a form of cancer that is linked to long term or high level exposure to asbestos, which is a known and potentially deadly carcinogenic that was once widely used in a range of applications.
The researchers work at the Brigham and Women’s Hospital in Boston, Massachusetts, and they claimed that they saw greater success when using sirolimus with cisplatin than they did when using cisplatin on its own. Sirolimus is currently being looked at for the treatment of a number of cancers including mesothelioma.
The drug acts as an inhibitor in the development of certain proteins that affect the growth of cells, cell survival and other factors that can affect the growth of cancers. It is thought that the benefits of the drug could make it easier to treat certain cancers.
Researchers at the hospital said that â€œSirolimus appears to enhance the cytotoxicity of cisplatin in malignant pleural mesothelioma cell lines through the mammalian target of rapamycin pathway. These results provide a basis for the clinical evaluation of combined sirolimus and cisplatin chemotherapy in malignant pleural mesothelioma.â€